Radiesse
A calcium-based biostimulator that prompts your own collagen and elastin.
What Radiesse Is
Radiesse is an injectable biostimulator composed of Calcium Hydroxylapatite (CaHA) microspheres suspended in a smooth gel carrier. CaHA is a biocompatible material similar to the mineral component naturally found in our bones and teeth.
Radiesse stimulates the body's natural collagen and elastin production, helping restore structural support, improve skin quality and address age-related changes in facial volume.
Radiesse can be administered using different techniques depending on your individual concerns and treatment goals.
How Radiesse Is Used
Treatment areas include the face, neck, décolletage and hands, depending on individual suitability.
Structural enhancement and volume restoration
In its more concentrated form, Radiesse can be used as a biostimulatory filler in specific facial areas to restore volume, enhance definition and provide structural support, while stimulating longer-term collagen production.
Diluted Radiesse, biostimulation
When diluted with saline, Radiesse is used primarily as a bio-stimulator rather than a volumising filler. It can be distributed across larger treatment areas to improve skin firmness, elasticity, texture and overall skin quality.
Understanding Cellular Activity
Following injection, the gel carrier provides an immediate volumising and lifting effect. As it gradually breaks down, the CaHA microspheres stimulate fibroblasts to produce new collagen and elastin, supporting improvements in skin firmness, elasticity and structure.
Senescent cells are aged or damaged cells that have stopped dividing but remain metabolically active. As they accumulate, they release inflammatory substances that can contribute to collagen breakdown, tissue degradation and visible signs of skin ageing. Radiesse stimulates fibroblast activity and new collagen production, helping support the surrounding tissue environment and counteract some of the structural changes associated with cellular ageing.
Quiescent cells are dormant cells that are not actively dividing but retain the ability to become active in response to tissue repair signals. These cells play an important role in maintaining and repairing skin tissue.
By stimulating the skin's regenerative processes, Radiesse encourages collagen production and supports the natural repair and renewal of the skin.
Super-hybrid Collagen Stimulating Protocol
Combining Neauvia Hydro Deluxe with Radiesse creates an advanced super-hybrid collagen-stimulating protocol.
Radiesse provides macro-particles of Calcium Hydroxyapatite (CaHA), while Hydro Deluxe contributes micro-trace CaHA. Together, they signal deep and superficial fibroblasts to remodel tissue.
The perfect partnership for faster results.
Think of Radiesse as a foreman waking up your skin's construction crew, the fibroblasts, and telling them to build new collagen. But a construction crew can't build a house without bricks and mortar. Hydro Deluxe delivers those exact bricks, the essential amino acids Glycine and L-Proline, straight to the site. This teamwork speeds up your skin's healing process and targets accelerated results.


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Radiesse® injectable implant is intended for plastic and reconstructive surgery, including deep dermal and sub-dermal soft tissue augmentation of the facial area and dorsum of the hands. Radiesse® injectable implant is indicated for: the treatment of nasolabial folds, marionette lines or jawline; the augmentation of cheeks; the hand augmentation to correct volume loss in the dorsum of the hands; and the restoration and/or correction of the signs of facial fat loss (lipoatrophy) in people with human immunodeficiency virus. Radiesse® (+) Lidocaine injectable implant is intended for plastic and reconstructive surgery, including deep dermal and sub-dermal soft tissue augmentation of the facial area and dorsum of the hands in adults. Radiesse® (+) Lidocaine injectable implant is indicated for: the treatment of nasolabial folds, marionette lines and jawline; the augmentation of cheeks; hand augmentation to correct volume loss in the dorsum of the hands; the restoration and/or correction of the signs of fat or volume loss (lipoatrophy) in the facial area and for rejuvenation of the hands fat loss (lipoatrophy) in people with human immunodeficiency virus.
You should tell your practitioner and avoid treatment with Radiesse® / Radiesse® (+) Lidocaine if you: have had an allergic reaction to any of the ingredients or have severe allergies including anaphylaxis; if you tend to develop keloids or heavy scars; have any bleeding disorders, poor wound healing; inflamed or infected skin; are under the age of 18; are pregnant or breastfeeding. Please inform your practitioner of any diseases you have or have had. These include in particular cardiovascular diseases, autoimmune diseases, diabetes, tumors, skin infections or severe allergies. If you take medication or vitamins, have had previous cosmetic procedures, or have been treated with other implants, please inform your practitioner. Always read the label and consult your Healthcare Professional for more information. This medical device must be administered by a Healthcare Professional. Merz Australia Pty Ltd (ACN: 151 073 559) Sydney, Australia. NZ Distribution: Pharmacy Retailing NZ Limited t/a Health Care Logistics (HCL). 58 Richard Pearse Drive, Mangere, Auckland 2022. For more information please phone 0800 822 310.

A biocompatible material similar to the mineral component naturally found in our bones and teeth.


